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Oxidative stress represents a condition, in which the production of free radicals exceeds the capacity of the antioxidant defenses to keep the levels below the toxic threshold

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Marcel Monnier and Lucien Hsli at Basel had reported, in cross-circulation experiments dating back to the 1960s, that low-frequency electrical stimulation of the intralaminar thalamic nuclei in donor rabbits produced a humoral factor that, when transferred to awake recipient rabbits via dialysed cerebral venous blood, induced an EEG pattern resembling slow-wave sleep

Downregulation of an evolutionary young miR-1290 in an iPSC-derived neural stem cell model of autism spectrum disorder